Table 2.

Mediation analysis using univariable Cox proportional hazards models with the primary composite outcome of cardiovascular events and death

SourceLog-Transformed BiomarkerProportion of Effect Explained (95% CI), %
PlasmaCK-MB12 (−17 to 41)
NT-proBNP34 (−2 to 70)
hs-cTnT21 (−11 to 53)
cTnI16 (−14 to 46)
H-FABP37 (−3 to 77)
All plasma49 (1 to 97)
UrineAlbumin8 (−3 to 18)
IL-18−3 (−19 to 13)
KIM-10 (−12 to 13)
L-FABP12 (−3 to 27)
NGAL1 (−12 to 14)
All urine1 (−18 to 19)