Table 1.

Baseline characteristics

Baseline CharacteristicAerobic Exercise/Caloric RestrictionUsual Activity/Caloric RestrictionAerobic Exercise/Usual DietUsual Activity/Usual Diet
N30282726
Age, yr53.5 (49.2 to 59.8)58.5 (45.8 to 62.0)58.0 (48.5 to 62.0)58.5 (45.8 to 64.0)
Men17 (56.7)15 (53.6)15 (55.6)17 (65.4)
Race
 White22 (73.3)19 (67.9)17 (63)16 (61.5)
 Black7 (23.3)9 (32.1)7 (25.9)8 (30.8)
 Other1 (3.3)0 (0)3 (11.1)2 (7.7)
Prevalent disease
 Congestive heart failure1 (3.3)2 (7.1)2 (7.4)0 (0)
 Myocardial infarction0 (0)0 (0)2 (7.4)0 (0)
 Coronary artery disease2 (6.7)2 (7.1)2 (7.4)0 (0)
 Diabetes mellitus7 (23.3)6 (21.4)7 (25.9)8 (30.8)
 Hypertension27 (90)26 (92.9)25 (92.6)22 (88)
Tobacco use
 Never18 (60)11 (39.3)7 (25.9)14 (56)
 Current3 (10)2 (7.1)3 (11.1)2 (8)
 Former9 (30)15 (53.6)17 (63)9 (36)
Systolic BP, mmHg128 (109 to 141)132 (118 to 141)134 (114 to 144)136 (118 to 142)
BMI, kg/m232.8 (30.4 to 35.8)32.8 (28.7 to 37.1)31.0 (28.0 to 36.2)35.5 (30.6 to 41.5)
Waist, in43.9 (41.3 to 45.3)41.1 (37.7 to 46.2)43.1 (40.8 to 46.4)45.5 (41.8 to 51.0)
Hip, in45.1 (42.1 to 48.0)45.0 (42.5 to 50.1)44.5 (41.6 to 47.9)47.5 (43.0 to 52.6)
DEXA body fat, %41.2 (35.0 to 45.5)42.4 (33.4 to 46.4)41.6 (36.7 to 45.4)40.5 (32.5 to 43.6)
VO2peak, ml/(kg·min)19.4 (16.2 to 24.4)19.7 (15.4 to 22.2)19.8 (16.8 to 22.4)19.3 (16.3 to 22.5)
Laboratory measurements
 eGFRcysC, ml/min per 1.73 m238.0 (28.1 to 54.9)39.1 (31.9 to 52.9)39.0 (32.4 to 51.9)33.2 (27.4 to 46.5)
 eGFRCKD-EPI, ml/min per 1.73 m241.9 (27.1 to 48.3)44.6 (31.9 to 52.9)44.0 (30.2 to 51.2)39.1 (31.1 to 49.8)
 IL-6, pg/ml1.37 (0.30 to 2.23)1.49 (0.04 to 2.64)1.27 (0.04 to 4.11)1.41 (0.36 to 3.44)
 F2-isoprostane, pg/ml28.0 (22.5 to 42.0)30.0 (21.0 to 37.0)31.5 (25.0 to 51.5)43.5 (31.0 to 60.0)
 Urine albumin-to-creatinine ratio, mg/g58.5 (22.0 to 362.2)29.6 (11.0 to 608.3)102.4 (16.6 to 834.2)65.6 (8.29 to 238.7)
  • Data are presented as median (interquartile range) or n (%). DEXA, dual energy x-ray absorptiometry.