Table 1.

Predonation characteristics of live kidney donors on the basis of APOL1 renal risk genotype

Predonation CharacteristicsHigh-Risk Genotype, n=19Low-Risk Genotype, n=117P Value
Age, yr37±937±90.84
Women, %61630.85
Weight, kg85±1682±180.49
Body mass index, kg/m230±529±60.45
Systolic BP, mm Hg121±7120±100.56
Diastolic BP, mm Hg72±873±80.61
Serum creatinine, mg/dl0.98±0.180.89±0.180.06
eGFR, ml/min per 1.73 m298±17108±200.03
Fasting blood sugars, mg/dl82±1281±120.62
Education, %0.09
 None to 8th grade111
 9th–11th Grade615
 High school4034
 Some college3338
Individual income, %0.97
Employed, full or part time, %83800.79
Family history of hypertension, yes, %79710.48
Family history of ESRD, yes, %89760.20
Relationship to the recipient, %0.27
  • High-risk genotype is defined as carrying two APOL1 renal risk alleles, and low-risk genotype is defined as carrying one or zero APOL1 renal risk alleles. Data are presented as mean±SD. To convert serum creatinine from milligrams per deciliter to micromoles per liter, multiply by 88.4. Family history of hypertension and ESRD was defined as first degree relative with these conditions.