Table 2.

Characteristics associated with NSG tuft volume in living kidney donors compared with patients who underwent a tumor nephrectomy

Clinical CharacteristicUnadjustedTest for Interaction
Kidney Donors (n=2453)Patients with Renal Tumor (n=780)
% DifferenceP Value% DifferenceP Value
Age per 10 yr (up to age 75 yr)0.00.99−1.60.240.30
Age per 10 yr (>75 yr)a−21.10.009
Men13.6<0.00119.3<0.0010.12
Height per SD5.9<0.0017.6<0.0010.27
BMI per SD10.8<0.0019.3<0.0010.30
Hypertension8.60.00110.7<0.0010.61
Diabetes22.6<0.001
eGFR per SD−1.40.120.70.580.18
Family history of ESRD7.4<0.001
24-h urine protein per doubling, mgb2.4<0.0014.1<0.0010.11
Tumor volume per doubling0.90.11
  • SD: 9.6 cm for height, 5.3 kg/m2 for body mass index (BMI), and 19.5 ml/min for eGFR.

  • a For patients with renal tumor, the change in the % difference for age up to 75 years compared with age >75 years was significant (P=0.04).

  • b Total N does not add up to 2453 or 780 because of missing data (n=2003 for donors, n=545 for patients with renal tumor).