Table 3.

Independent clinical characteristics associated with NGS tuft volume in both kidney donors and patients with renal tumor up to age 75 years

Clinical CharacteristicMultivariable Adjusteda
Kidney Donors and Patients with Renal Tumor (n=2447)
% DifferenceP Value
Age per 10 yr (up to age 75 yr)0.10.93
Men9.5<0.001
Height per SD2.10.04
BMI per SD8.4<0.001
Hypertension3.80.09
Diabetes13.60.008
eGFR per SD1.90.06
Family history of ESRD7.3<0.001
24-h urine protein per doubling, mgb2.5<0.001
Patients with renal tumor versus kidney donors1.80.49
  • The mean SD across both populations was used (9.6 cm for height, 5.3 kg/m2 for body mass index [BMI], 19.5 ml/min for eGFR).

  • a Adjusted for each other characteristic.

  • b If 24-hour urine protein was excluded, findings were similar except hypertension was also associated with larger NSG tuft volume (6.2% larger; P=0.002).