Table 1.

Characteristics at study entry in participants who did or did not develop incident AF

CharacteristicIncident AF, n=323No Incident AF, n=2757P Value
Age, mean (SD), yr61.6 (9.2)57.3 (11.2)<0.001
Women, N (%)129 (39.9)1258 (45.6)0.05
Race/ethnicity, N (%)
 Non-Hispanic white165 (51.1)1156 (41.9)0.009
 Non-Hispanic black119 (36.8)1120 (40.6)
 Hispanic30 (9.3)365 (13.2)
 Other9 (2.8)116 (4.2)
Diabetes mellitus, N (%)171 (52.9)1290 (46.8)0.04
Hypertension, N (%)298 (92.3)2341 (84.9)<0.001
Prior MI or coronary revascularization, N (%)103 (31.9)449 (16.3)<0.001
History of stroke, N (%)36 (11.1)231 (8.4)0.10
History of HF, N (%)38 (11.8)145 (5.3)<0.001
History of peripheral vascular disease, N (%)24 (7.4)158 (5.7)0.22
Any prior CVD, N (%)143 (44.3)723 (26.2)<0.001
Current smoker, N (%)41 (12.7)361 (13.1)0.84
Systolic BP, mean (SD), mm Hg131.9 (21.9)127.7 (21.7)0.001
BMI, mean (SD), kg/m233.0 (7.9)31.8 (7.7)0.01
eGFR, ml/min per 1.73 m2, N (%)
 <3078 (24.1)514 (18.6)<0.001
 30–44127 (39.3)885 (32.1)
 45–5981 (25.1)814 (29.5)
 ≥6037 (11.5)544 (19.7)
Urine protein, median (IQR), g/24 h0.2 (0.1–0.9)0.2 (0.1–1.0)0.27
Aspirin use, N (%) 167 (51.7)1130 (41.0)<0.001
Antiplatelet use, N (%)177 (54.8)1212 (44.0)<0.001
Warfarin use, N (%)20 (6.2)59 (2.1)<0.001
FGF23, median (IQR), RU/ml163.7 (109.2–255.0)135.5 (91.7–219.3)<0.001
hs-CRP, median (IQR), mg/L3.4 (1.3–7.6)2.4 (1.0–5.9)<0.001
NT-proBNP, median (IQR), pg/ml326.7 (120.2–678.2)120.2 (53.8–291.6)<0.001
hsTnT, median (IQR), pg/ml ECG parameters16.5 (9.1–32.5)10.7 (5.1–20.9)<0.001
 Left ventricular hypertrophy, N (%)158 (65.3)969 (47.4)<0.001
 Left ventricular mass index, median (IQR), g/m255.4 (46.7–64.3)47.8 (40.7–57.3)<0.001
 Left atrial diameter, mean (SD), cm4.1 (0.7)3.9 (0.6)<0.001
 Left ventricular ejection fraction, median (IQR)54.5 (49.0–57.8)55.5 (51.9–59.3)<0.001
  • IQR, interquartile range.