Table 3.

Hazard ratios with 95% confidence intervals from multivariable regression analyses of the association of sex (women versus men) with all-cause mortality

ModelVariables Included in Regression ModelsDeath from Any CauseDeath from Any Cause (ESRD as a Censoring Event)
Model 1Clinical site, age, race/ethnicity, baseline eGFR, and urine protein-to-creatinine ratio0.69 (0.60 to 0.80)0.78 (0.70 to 0.86)
Model 2+Education, marital status, nephrology care, health insurance0.61 (0.51 to 0.73)0.70 (0.62 to 0.79)
Model 3+Smoking status, physical activity, BMI, waist circumference0.65 (0.54 to 0.80)0.76 (0.66 to 0.86)
Model 4+Systolic BP, diabetes, CVD, LDL, HDL, triglycerides, albumin, and hemoglobin0.65 (0.52 to 0.81)0.67 (0.58 to 0.78)
Model 5+ACEi/ARB, aspirin, and statin0.65 (0.52 to 0.81)0.68 (0.58 to 0.78)
Model 6+Serum FGF23, calcium, and phosphorus0.56 (0.44 to 0.70)0.64 (0.55 to 0.74)
  • BMI, body mass index; CVD, cardiovascular disease; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; FGF23, fibroblast growth factor 23.