Table 5.

Comparison of mean scores and validity statistics by self-evaluated severity of kidney disease symptomsa

MeasureMean (SD) ScoreF Statisticη2bRV (95% CI)
Not Notable, n=148Mild, n=120Moderate, n=131Severe, n=50
KDQOL-36
 Burden (+)81.6 (22.9)63.8 (23.1)48.0 (25.7)31.6 (25.2)74.5c0.331.0
 Effects (+)86.9 (13.2)75.9 (17.4)61.6 (21.6)52.8 (23.7)66.2c0.310.89 (0.65 to 1.21)
 Symptoms (+)86.1 (10.8)79.4 (12.5)68.0 (16.0)62.5 (18.3)58.6c0.280.79 (0.53 to 1.16)
CKD-QOL
 CKD-QOL-6 (−)40.0 (5.3)45.6 (6.4)52.9 (7.7)56.5 (8.4)123.0c0.451.65 (1.24 to 2.21)d
 CKD-QOL-CAT (−)37.8 (7.2)45.9 (7.3)53.0 (7.7)56.3 (6.3)136.2c0.481.83 (1.36 to 2.45)d
 Three- or six-item CAT (−)38.6 (6.2)45.9 (7.5)53.2 (8.0)56.5 (6.5)131.7c0.471.77 1.29 to 2.39)d
SF-12v2
 PCS (+)46.6 (9.7)42.6 (9.8)35.1 (9.9)32.5 (9.7)45.1c0.230.61 (0.37 to 0.95)d
 MCS (+)53.8 (9.1)50.7 (10.1)47.6 (9.8)46.1 (11.8)12.6c0.080.17 (0.07 to 0.31)d
  • Means are unadjusted. 95% CI, 95% confidence interval.

  • a Self-reported response to “How would you rate the severity of your kidney disease symptoms in the past 4 weeks?”: not noticeable, mild, moderate, severe/very severe.

  • b η2 estimate of variance explained by groups (see text); significance is same as F ratio.

  • c P<0.001 (see text).

  • d P<0.05 (see text).