Table 1.

Demographics of children at study entry (only includes those with 1-year follow-up)

DemographicsHDHDFP-Value
Number7855
Age, yr, n (%)0.45
 5–1017 (21.8)14 (25.5)
 10–1527 (34.6)23 (41.8)
 15–2034 (43.6)18 (32.7)
Females, n (%)32 (41.0)31 (56.4)0.08
Race, %
 White/Asian/black/Mixed or other75.6/6.4/5.2/12.870.9/10.9/10.9/7.30.48
Anthropometry
 Height SD score−2.24 (−3.08 to −1.04)−1.66 (−2.94 to −0.91)0.21
 Body mass index SD score−0.11 (−0.85 to +0.92)−0.17 (−0.96 to +0.77)0.61
Underlying renal diagnosis, %
 Dysplasia/GN/cystic kidney disease/others or unknown42.3/20.5/3.9/33.338.2/20.0/5.5/36.30.66
Comorbidity/genetic conditions, n (%)0.76
 Impaired cognitive development15 (19.2)13 (23.6)
 Impaired motor development5 (6.4)6 (10.9)
 Ocular or hearing abnormalities12 (15.4)11 (20.1)
 Cardiopulmonary5 (6.4)7 (12.7)
 Other abnormalities20 (25.6)13 (23.6)
 Genetic disorder/defined syndrome17 (21.8)17 (30.9)
Previous dialysis
 Incident patients in study, %52 (66.7)28 (51)0.11
If previous dialysis
 PD/HD/HDF/HD and PD sequentially13/7/1/512/3/7/40.43
Time on dialysis before start of 3H study
 Incident patients, mo1.03 (0.2–1.7)1.4 (0.61–1.9)0.69
 Prevalent patients, mo24.5 (18–52)29.5 (17–53.3)0.91
Previous transplant
 Yes, %14 (18.0)15 (27.3)0.20
 Time with functioning graft, mo30 (14–72)72 (10–119)0.34
Vascular access, n (%)
 Central venous line/arteriovenous fistula/arteriovenous graft49 (62.8)/28 (35.9)/1 (1.3)30 (54.6)/23 (41.8)/2 (3.6)0.48
Blood flow, ml/min200 (180–250)200 (170–250)0.38
Blood flow corrected for body surface area190.3 (157.7–214.8)183.7 (141.2–225.1)0.96
Residual renal function (urine volume in ml; %)
 032 (41.0)21 (38.2)
 0–20018 (23.1)7 (12.7)0.32
 201–50011 (14.1)9 (16.4)
 500+17 (21.8)18 (32.7)
Dialysis prescription
 Time on dialysis, h/wk12 (11.83–12.20)12 (11.81–12.22)0.96
 Dialyzer, high/mid/low flux (%)57 (73)/9 (15)/12 (12)55 (100)<0.001
 Water quality, ultrapure (%)40 (51.2)55 (100)<0.001
Dialysate sodium, %0.39
 ≤138 mmol/L versus ≥138 mmol/L56 (71.8)/22 (28.2)37 (67.3)/18 (32.7)
Dialysate calcium0.78
 1.25 versus 1.5 versus 1.75 mmol, %48 (62)/24 (30)/6 (8)34 (62)/18 (33)/3 (5)
Dialysate bicarbonate <34 versus 34–36 versus >36 mmol/L, %34 (44)/34 (44)/10(12)23 (41)/34 (56)/10 (4)0.74
  • Data are presented as number (n) with percentage or as median and interquartile range. All dialysis-related parameters are expressed as the mean of the previous four midweek dialysis sessions. PD, peritoneal dialysis.