Table 2.

Characteristics of colonic polyps in screen positive participants who underwent work-up colonoscopy (n=223)

CharacteristicsAllCKD Stages 3–5DialysisTransplantP Valuea
Participants with polyps223 (100)95 (42.6)66 (29.6)62 (27.8)0.03
Polyps per patientb
 1 polyp83 (37.2)34 (35.8)17 (25.8)32 (51.6)0.01
 2–3 polyps90 (40.4)38 (40.0)29 (43.9)23 (37.1)0.7
 >3 polyps50 (22.4)23 (24.2)20 (30.3)7 (11.3)0.03
Location of the largest polyp
 Cecum36 (16.1)23 (24.2)4 (6.1)9 (14.5)0.01
 Ascending colon35 (15.7)18 (18.9)11 (16.7)6 (9.7)0.3
 Transverse colon33 (14.8)9 (9.5)17 (25.8)7 (11.3)0.01
 Descending colon22 (9.9)7 (7.4)9 (13.6)6 (9.7)0.4
 Sigmoid colon/rectum95 (42.6)37 (38.9)24 (36.4)34 (54.8)0.07
 Other2 (0.9)1 (1.1)1 (1.5)00.6
Size of the largest polyp, mm
 <540 (17.9)17 (17.9)10 (15.2)13 (21.0)0.7
 5–10124 (55.6)53 (55.8)39 (59.1)32 (51.6)0.7
 >1059 (26.5)25 (26.3)17 (25.8)17 (27.4)0.9
Neoplastic lesionsc
 Tubulovillous adenomas62 (27.8)30 (31.6)16 (24.2)16 (25.8)0.5
 Tubular adenomas149 (66.8)62 (65.3)46 (69.7)41 (66.1)0.8
 Villous adenomas3 (1.3)2 (2.1)01 (1.6)0.5
 Sessile serrated adenomas/polyps10 (4.5)6 (6.3)1 (1.5)3 (4.8)0.6
Non-neoplastic lesionsc
 Inflammatory polyps7 (3.1)1 (1.1)3 (4.5)3 (4.8)0.3
 Hyperplastic/others44 (19.7)16 (16.8)18 (27.3)10 (16.1)0.5
Advanced neoplasiab103 (46.1)44 (46.3)31 (47.0)28 (45.2)0.9
Colorectal cancers7 (3.1)2 (2.1)3 (4.5)2 (3.2)0.7
  • a P values are on the basis of chi-square analyses for comparison between the three groups (CKD stages) in each row.

  • b Advanced colorectal neoplasia was defined as any colorectal adenoma with at least one of the following features: ≥1 cm in size, villous component (≥25%) or high-grade dysplasia; or any serrated lesion ≥1 cm in diameter, or with dysplastic component; or any invasive colorectal cancer.

  • c Participants can have more than one of the neoplastic and non-neoplastic lesions.