Table 1.

Baseline patient characteristics (full analysis set)

Summary StatisticSZC, n=97PBO, n=99Total, n=196
Demographics/baseline characteristic
 Age, yr
  n9799196
  Mean55.760.458.1
  SD13.813.213.7
 Age group, yr, n (%)
  18–5031 (32.0)21 (21.2)52 (26.5)
  51–6434 (35.1)32 (32.3)66 (33.7)
  65–8432 (33.0)45 (45.5)77 (39.3)
  ≥850 (0.0)1 (1.0)1 (0.5)
  Total97 (100.0)99 (100.0)196 (100.0)
 Sex, n (%)
  Men57 (58.8)58 (58.6)115 (58.7)
  Women40 (41.2)41 (41.4)81 (41.3)
 Race, n (%)
  White50 (51.5)52 (52.5)102 (52.0)
  Black or African American11 (11.3)8 (8.1)19 (9.7)
  Asian33 (34.0)33 (33.3)66 (33.7)
  American Indian or Alaska Native1 (1.0)2 (2.0)3 (1.5)
  Other2 (2.1)4 (4.0)6 (3.1)
 Height, cm
  n9799196
  Mean166.4165.1165.7
  SD9.99.29.5
 Weight, kg
  n9799196
  Mean72.070.071.0
  SD22.015.919.1
 BMI, kg/m2
  n9799196
  Mean26.926.726.8
  SD7.15.46.3
Dialysis history
 Vintage, yr
  n9297189
  Mean8.07.87.9
  SD6.17.66.9
 Access type, n (%)
  Arteriovenous fistula84 (87.5)90 (90.9)174 (89.2)
  Arteriovenous graft7 (7.3)3 (3.0)10 (5.1)
  Tunneled central venous catheter4 (4.2)6 (6.1)10 (5.1)
  Other1 (1.0)0 (0.0)1 (0.5)
  Total96 (100.0)99 (100.0)195 (100.0)
Dialysis parameters
 spKt/V
  n7471
  Mean1.71.7
  SD0.30.4
 Urea removal rate, %
  n5258
  Mean72.974.6
  SD6.75.6
 Dialysate flow, mL/min
  n9699
  Mean512.0538.5
  SD162.8136.0
 dK+ concentration, mmol/L
  n9699
  Mean2.32.3
  SD0.50.5
  Minimum, maximum1.0, 3.01.0, 3.0
 Blood flow, mL/min
  n9699
  Mean322.0318.5
  SD110.796.3
  • SZC, sodium zirconium cyclosilicate; PBO, placebo; BMI, body mass index; spKt/V, single-pool Kt/V; dK+, dialysate potassium.