Table 1.

Baseline characteristics

CharacteristicFerric Citrate (n=133)SOC (n=66)Significance
eGFR<15, %5558NS
eGFR 15–20, %4542NS
Mean age±SD, yr63.1±1361.1±12NS
Race, %
 White7970
 Black1527
Male sex, %6262NS
Hispanic ethnicity, %1418NS
Primary cause, %
 Diabetes3564
 HTN169
Comorbidity, %
 Congestive heart failure 2130NS
 Diabetes mellitus47770.001
 Coronary artery disease2724NS
 Hypertension9692NS
 Myocardial infarction1512NS
 Peripheral vascular disease9270.001
 Cerebrovascular disease1311NS
 Fracture89NS
 Secondary hyperparathyroidism8886NS
 Dyslipidemia8382NS
 Anemia9594NS
Transplant status, %NS
 Active on list2011
 Referred to transplant3544
 Not candidate2024
Laboratory (mean±SD)
 eGFR, ml/min per 1.73 m214.2±3.914.5±4.1NS
 Ferritin, ng/ml202±173170±1690.04
 Hemoglobin, g/dl11.3±1.611±1.6NS
 Transferrin saturation, %25±923±90.04
 P, mg/dl4.5±0.94.4±0.7NS
 25D, ng/ml30±1129±12NS
 1,25D, pg/ml28±1324±9NS
 PTH, pg/ml207±152213±178NS
 Median intact FGF23 (25–75), pg/ml352 (222–552)331 (229–704)NS
  • 25–75, 25th–75th percentile; HTN, hypertension.