Banff allograft pathology quantitative scores and other pathologic characteristics
| Case | i (%) | ti (%) | i-IFTA (%) | ci (%) | ct (%) | t | v | i | ti | i-IFTA | g | ci | ct | cg | mm | cv | ah | ptc | C4d | Diagnosis | g+ptca |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| H27P | 60 | 70 | 70 | 70 | 70 | 2 | 0 | 3 | 3 | 3 | 2 | 3 | 3 | 0 | 1 | 0 | 0 | 2 | 1 | ACR, type 1A, peri-glomerular inflammation/Bowman’s capsulitis leads to crescent formation | 4 |
| H14C | 20 | 20 | 75 | 6 | 1 | 3 | 0 | 1 | 1 | 3 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | “Borderline changes” “suspicious” for ACR (inflammation is patchy, focused in selected areas where it is very intense) | 3 |
| G25H | 5 | 5 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 1 | 3 | Thrombotic microangiopathy with findings suspicious of AMR; no evidence of ACR | 3 |
| H916 | 30 | 30 | 30 | 10 | 3 | 2 | 1 | 2 | 2 | 2 | 3 | 1 | 1 | 3 | 3 | 1 | 0 | 3 | 2 | ACR, type 2A; findings also suspicious for chronic, active AMR. Transplant glomerulopathy with focal crescent formation | 6 |
| H920 | 5 | 5 | 15 | 6 | 1 | 1 | 1 | 0 | 0 | 1 | 3 | 1 | 1 | 3 | 3 | 0 | 0 | 3 | 1 | ACR, type 2A (due to quite focal endarteritis); findings also suspicious for chronic, active AMR. Transplant glomerulopathy is present | 6 |
| H34V | 40 | 40 | 55 | 15 | 10 | 2 | 0 | 2 | 2 | 3 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 2 | ACR, type 1A; findings are also suspicious for AMR. Neutrophil casts are also suggestive of a urinary tract infection | 5 |
i, interstitial inflammation; ti, total inflammation; i-IFTA, cortical inflammation; ci, cortical interstitial fibrosis; ct, cortical tubular atrophy; t, tubulitis; v, intimal arteritis; g, allograft glomerulitis; cg, allograft glomerulopathy; mm, mesangial matrix; cv, vascular fibrous intimal thickening; ah, arteriolar hyalinosis; ptc, peritubular capillary inflammation; C4d, complement breakdown product that deposits in peritubular capillaries and medullary vasa recta; g+ptc, microcirculation inflammation; ACR, acute cellular rejection.
↵a If ≥2, suspicious of AMR.