Table 1.

Banff allograft pathology quantitative scores and other pathologic characteristics

Casei (%)ti (%)i-IFTA (%)ci (%)ct (%)tvitii-IFTAgcictcgmmcvahptcC4dDiagnosisg+ptca
H27P607070707020333233010021ACR, type 1A, peri-glomerular inflammation/Bowman’s capsulitis leads to crescent formation4
H14C2020756130113211010010“Borderline changes” “suspicious” for ACR (inflammation is patchy, focused in selected areas where it is very intense)3
G25H5552000000200330013Thrombotic microangiopathy with findings suspicious of AMR; no evidence of ACR3
H91630303010321222311331032ACR, type 2A; findings also suspicious for chronic, active AMR. Transplant glomerulopathy with focal crescent formation6
H92055156111001311330031ACR, type 2A (due to quite focal endarteritis); findings also suspicious for chronic, active AMR. Transplant glomerulopathy is present6
H34V404055151020223211000032ACR, type 1A; findings are also suspicious for AMR. Neutrophil casts are also suggestive of a urinary tract infection5
  • i, interstitial inflammation; ti, total inflammation; i-IFTA, cortical inflammation; ci, cortical interstitial fibrosis; ct, cortical tubular atrophy; t, tubulitis; v, intimal arteritis; g, allograft glomerulitis; cg, allograft glomerulopathy; mm, mesangial matrix; cv, vascular fibrous intimal thickening; ah, arteriolar hyalinosis; ptc, peritubular capillary inflammation; C4d, complement breakdown product that deposits in peritubular capillaries and medullary vasa recta; g+ptc, microcirculation inflammation; ACR, acute cellular rejection.

  • a If ≥2, suspicious of AMR.