Table 1.

Baseline characteristics of the 2293 donors

Clinical CharacteristicMean (SD) or n (%)
Age at transplant surgery, yr43.8 (11.9)
Male930 (40.6%)
Race
 Black77 (3.4%)
 White1898 (82.8%)
 Other/unknown318 (13.9%)
BMI, kg/m227.5 (4.8)
Height, cm170.4 (9.6)
Measured GFR, ml/min per 1.73 m2114.7 (24.4)
24 h urine albumin, mga4.3 (10.9)
Living related donor1189 (51.9%)
Hypertension359 (15.7%)
Biopsy featuresb
 Globally sclerotic glomeruli, %3.3 (6.3)
 Glomerulosclerosis above age thresholdc138 (6.0%)
 %IF/TA
  0%1670 (72.9%)
  >0% to ≤5%552 (24.1%)
  >5%69 (3.0%)
 Number of IF/TA foci per mm20.1 (0.2)
 Artery luminal stenosis, %34.1 (21.0)
 Tubular cross-sectional area, per 1000 µm24.2 (1.4)
 Nonsclerotic glomeruli volume, per 1000 mm32.5 (1.0)
 Cortical volume per glomerulus, mm30.1 (0.0)
 Presence of any arteriolar hyalinosisd213 (13.4%)
CT features
 Cortex volume, cm3102.3 (21.4)
 Medullary volume, cm342.2 (10.6)
 Any kidney cyst (>1 cm in diameter)207 (9.0%)
 Kidney surface roughness score
  0862 (37.6%)
  1557 (24.3%)
  2492 (21.5%)
  3381 (16.6%)
Nephron number, per 1000929.9 (439.9)
Single-nephron GFR, nl/min76.1 (47.5)
  • a Assessed in 1705 donors.

  • b Biopsies used had a mean±SD cortical area of 6.7±3.0 mm2 and number of glomeruli of 19±11 per section.

  • c Number of globally sclerotic glomeruli on biopsy exceeds 95th percentile expected for donor age and number of glomeruli present.30

  • d Assessed in 1585 donors.