Table 2.

Risk factors for ICPi-AKI

Baseline VariablesOdds Ratio (95% Confidence Interval) for ICPi-AKI
UnivariateMultivariateForest Plot
Age (per 10 years)1.08 (0.92 to 1.26)0.91 (0.75 to 1.11)Embedded Image
Female1.08 (0.71 to 1.64)1.05 (0.67 to 1.65)
Prior autoimmune disease1.15 (0.61 to 2.18)1.08 (0.55 to 2.11)
eGFR, per 30 ml/min per 1.73 m2 decline1.67 (1.27 to 2.17)1.99 (1.43 to 2.76)
PPI use2.38 (1.57 to 3.62)2.85 (1.81 to 4.48)
Combination ICPi therapy2.71 (1.62 to 4.53)3.88 (2.21 to 6.81)
  • The full multivariable model was adjusted for the covariates listed in the table.