Table 2.

Clinical characteristics of patients with COVID-19 according to the severity of disease

CharacteristicsTotal (n=131)Mild/Moderate (n=101)Severe/Critical (n=30)P Value
Symptoms, n (%)
 Fever68 (51.9)46 (45.5)22 (73.3)0.008
 Fatigue59 (45.0)41 (40.6)18 (60.0)0.06
 Cough49 (37.4)29 (28.7)20 (66.7)<0.001
 Sputum production38 (29.0)23 (22.8)15 (50.0)0.004
 Dyspnea34 (26.0)19 (18.8)15 (50.0)<0.001
 Nausea/vomiting18 (13.7)10 (9.9)8 (26.7)0.03a
 Diarrhea17 (13.0)11 (10.9)6 (20.0)0.22a
 Sore throat10 (7.7)6 (5.9)4 (13.8)0.23a
BP (mm Hg), mean (SD)
 Systolic BP147.5 (22.0)147.0 (23.5)148.8 (17.9)0.71
 Diastolic BP82.1 (13.1)82.9 (12.3)80.3 (15.0)0.36
Radiologic findings
 CT scan image features, n (%)0.01a
  Ground-glass/patchy opacity96 (82.1)72 (81.8)24 (82.8)
  Cord shadow9 (7.7)8 (9.1)1 (3.5)
  Consolidation5 (4.3)1 (1.1)4 (13.8)
  Other7 (6.0)7 (8.0)0 (0.0)
Lesion region, n (%)0.71a
 Bilateral lung98 (86.7)71 (84.5)27 (93.1)
 Left lung7 (6.2)6 (7.1)1 (3.5)
 Right lung8 (7.1)7 (8.3)1 (3.5)
Laboratory findings, median (IQR)
 Hemoglobin (g/L)105.0 (91.0–118.0)106.0 (91.0–119.0)99.9 (82.0–116.0)0.28b
 PLT (109/L)144.2 (107–186)142.0 (108.0–184.5)147.5 (100.0–213.0)0.68b
 White blood cells (109/L)5.0 (3.8–7.3)4.8 (3.7–7.2)5.7 (4.5–7.7)0.18b
 Lymphocytes (109/L)0.7 (0.5–1.1)0.8 (0.5–1.1)0.5 (0.3–1.2)0.19b
 Neutrophils (109/L)3.9 (3.0–6.1)3.7 (2.6–5.6)5.3 (3.4–6.6)0.09b
 Albumin (g/L)37.7 (34.0–40.7)38.0 (34.2–40.8)36.8 (33.4–39.7)0.31b
Complications, n (%)
 Cardiac injury (n=85)24 (28.2)16 (25.8)8 (34.8)0.41
 Liver dysfunction (n=103)16 (15.5)7 (9.1)9 (34.6)0.004a
 Cerebrovascular event (n=94)9 (9.6)7 (10.1)2 (8.0)0.99a
 ARDS (n=116)16 (13.8)4 (4.5)12 (44.4)<0.001a
  • P values were calculated by the t test or Wilcoxon test for continuous variables, and the chi-squared test for categorical variables, otherwise Fisher’s exact test was used when the data were limited. PLT, platelet.

  • a P values from Fisher’s exact test.

  • b P values from the Wilcoxon test.