Clinical findings in patients with COVID-19 who underwent kidney biopsy
| Pt | Age | Sex | Race | Comorbidities | IS | Temperature, °C | SpO2 on RA | BP | Edema | COVID-19 Manifestations | Renal Presentation/Biopsy Indications |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 46 | M | B | OSA, obesity (BMI=44) | N | 37.1 | 94 | 144/100 | Y | Cough, fever, sore throat | AKI, NS |
| 2 | 62 | M | B | HTN, prostate carcinoma | N | 37.2 | 98 | 126/79 | Y | Fever, myalgia, weakness | AKI on CKD, NS |
| 3 | 62 | M | B | HTN, DM, prostate carcinoma | N | 36.8 | 91 | 122/82 | N | Fever, hypoxemia, bilateral perihilar and basilar infiltrates on CXR | AKI, NRP |
| 4 | 57 | M | B | HTN, untreated hepatitis C virus | N | 38.1 | 97 | 173/92 | N | Flu-like symptoms with ground glass opacities and patchy consolidation on CXR | AKI on CKD, NRP |
| 5 | 61 | M | B | HTN, obesity (BMI=31.1) | N | 38.5 | 99 | 134/79 | N | Cough, fever | AKI, NRP |
| 6 | 25 | M | B | Obesity (BMI=32.2) | N | 38.5 | 95 | 117/79 | Y | Cough, fever, myalgia, infiltrates on CXR | AKI, NS |
| 7 | 43 | F | B | DM, HLD, streptococcal infection, obesity (BMI=52.5) | N | 37.6 | 96 | 107/67 | N | Cough, fever, sore throat, weakness, patchy LUL infiltrates on CXR | AKI |
| 8 | 28 | M | B | None | N | 38.6 | 96 (on O2) | 143/62 | N | Cough, fever, hypoxemia, bilateral infiltrates on CXR, elevated troponin and CPK | AKI |
| 9 | 67 | M | W | HTN, gout, history of tobacco use, obesity (BMI=34.9) | N | 36.5 | 95 | 135/75 | N | Cough, diarrhea, lethargy, multifocal infiltrates on CXR | AKI on CKD |
| 10 | 51 | M | B | HTN, DSA+ OHTx for NICM 1 yr ago, atrial fibrillation, CVA, BPH, HLD | Y | 36.8 | 96 | 117/81 | N | Predominantly nausea, vomiting, abdominal pain, with cough | AKI on CKD |
| 11 | 72 | M | W | HTN, DM, HLD, gout, spinal stenosis, atrial fibrillation | N | 36.8 | 97 (on O2) | 125/73 | Y | Cough, pleural effusion on CT | NS |
| 12 | 70 | F | B | HTN, CAD, PVD, cervical carcinoma, GERD, HLD, obesity (BMI=39.4) | N | 38.1 | 92 | 118/58 | Y | Cough, fever, shortness of breath | AKI, NRP |
| 13 | 27 | F | A | SLE with class 2 lupus nephritis | Y | 36.9 | 93 | 130/80 | Y | Cough, fever, shortness of breath, hypoxemia, bilateral infiltrates on CXR, required intubation and ICU admission | AKI, NS |
| 14 | 48 | F | B | GERD, history of tobacco use, obesity | N | 37.6 | 98 | 185/80 | N | Cough, myalgia, infiltrates on CXR | AKI |
| 15 | 54 | M | W | ESKD secondary to IgAN s/p DSA+ LURTx 1 mo ago, HTN, obesity (BMI=30.7) | Y | 36.8 | 99 | 116/75 | N | Asymptomatic | AKI |
| 16 | 22 | M | B | ESKD likely secondary to PLA2R+ MGN s/p DDRTx 2 years ago, HTN | Y | 37.7 | 95 | 178/127 | N | Cough, fever, bilateral infiltrates on CXR, required intubation and ICU admission | CKD |
| 17 | 54 | F | H | ESKD secondary to PCKD s/p DDRTx 2 months ago, HTN | Y | 98.8 | 100 | 104/70 | N | Fever, dry throat | AKI |
BP is in millimeters of Hg. Pt, patient; IS, immunosuppression at presentation; SpO2, oxygen saturation (percentage); RA, room air; M, man; B, black; OSA, obstructive sleep apnea; BMI, body mass index; N, no; Y, yes; NS, nephrotic syndrome; HTN, hypertension; AKI on CKD, AKI superimposed on CKD; DM, diabetes mellitus; CXR, chest x-ray; NRP, nephrotic-range proteinuria; F, woman; HLD, hyperlipidemia; LUL, left upper lobe; O2, oxygen; CPK, creatine phosphokinase; W, white; DSA, donor-specific antibody; OHTx, orthotopic heart transplantation; NICM, nonischemic cardiomyopathy; CVA, cerebrovascular accident; BPH, benign prostatic hyperplasia; CT, computed tomography; CAD, coronary artery disease; PVD, peripheral vascular disease; GERD, gastroesophageal reflux disease; A, Asian; ICU, intensive care unit; IgAN, IgA nephropathy; s/p, status post; LURTx, living unrelated renal transplantation; MGN, membranous glomerulopathy; DDRTx, deceased donor renal transplantation; H, Hispanic; PCKD, polycystic kidney disease.