Table 3.

The treatment and outcome of patients during the hospitalization

Treatment and OutcomeTotal (n=81)Presence of AKISurvival
AKI (n=41)Non-AKI (n=40)P ValueNonsurvivors (n=60)Survivors (n=21)P Value
Therapies, n (%)
 Glucocorticoids71 (87.7%)34 (82.9%)37 (92.5%)0.3154 (90.0%)17 (81.0%)0.28
 Antiviral medication66 (81.5%)33 (80.5%)33 (82.5%)0.8249 (81.7%)17 (81.0%)0.94
 Antibiotics75 (92.6%)38 (92.7%)37 (92.5%)>0.9957 (95.0%)18 (85.7%)0.18
 Intravenous Ig66 (81.5%)33 (80.5%)33 (82.5%)0.8248 (80.0%)18 (85.7%)0.75
 Blood transfusion22 (27.2%)14 (34.1%)8 (20.0%)0.1518 (30.0%)4 (19.0%)0.40
 Anticoagulation41 (50.6%)21 (51.2%)20 (50.0%)0.9129 (48.3%)12 (57.1%)0.49
 Anti-inflammatory therapies13 (16.0%)8 (19.5%)5 (12.5%)0.399 (15.0%)4 (19.0%)0.73
Life-sustaining treatment, n (%)
 Invasive mechanic ventilation66 (81.5%)36 (87.8%)30 (75.0%)0.1453 (88.3%)13 (61.9%)0.007
 ECMO5 (6.2%)2 (4.9%)3 (7.5%)0.683 (5.0%)2 (9.5%)0.60
 Vasopressors63 (77.8%)36 (87.8%)27 (67.5%)0.03a56 (93.3%)7 (33.3%)<0.001a
 CRRT8 (9.9%)8 (19.5%)0 (0.0%)8 (13.3%)0 (0.0%)
Outcome, n (%)
 Death60 (74.1%)34 (82.9%)26 (65.0%)0.07
 Survive before this study21 (25.9%)7 (17.1%)14 (35.0%)
Time from illness to admission (d), median (IQR)9.0 (5.5–13.5)8.0 (5.0–11.0)10.5 (7.0–16.0)0.099.0 (5–11.8)11.0 (6.0–16.5)0.11
Time from illness to intubation (d), median (IQR)b15.5 (12.0–21.0)14.0 (11.0–20.8)17.0 (13.0–23.5)0.1316.0 (12.5–21.0)13.0 (10.0–22.5)0.65
Time of mechanic ventilation (d), median (IQR)b9.5 (3.8–16.5)10.0 (3.0–18.0)9.0 (4.0–15.0)0.898 (3.0–13.5)27.0 (13.5–41.0)<0.001a
Time from illness to AKI (d), median (IQR)c21.0 (9.5–26.0)21.0 (9.5–26.0)20.5 (9.0–24.2)21.0 (15.0–35.0)0.40
Time from illness to death (d), median (IQR)d24.0 (18.0–31.8)24.0 (18.0–32.2)24.5 (18.8–31.0)0.9624.0 (18.0–31.8)
Time of hospitalization (d), median (IQR)17.0 (10.0–26.0)18.0 (10.0–28.0)15.5 (9.5–23.8)0.7614.0 (9.2–22.8)29.0 (14.5–39.0)<0.001a
Disease course before this study (d), median (IQR)28.0 (19.0–36.0)26.0 (18.0–36.0)28.5 (19.2–38.2)0.4224.0 (18.0–31.8)39.0 (29.0–52.5)<0.001a
  • ECMO, extracorporeal membrane oxygenation.

  • a P<0.05.

  • b All patients, n=66; AKI, n=30; non-AKI, n=36; nonsurvivors, n=53; survivors, n=13.

  • c All patients, n=41; nonsurvivors, n=34; survivors, n=7.

  • d All patients, n=60; AKI, n=34; non-AKI, n=26.