Table 5.

Univariate and multivariable analysis by logistic regression on factors associated with AKI in patients infected by SARS-CoV and SARS-CoV-2 separately

ParametersSARS-CoV n=1565SARS-CoV-2 n=814
Univariate analysisMultivariable analysisaUnivariate analysisMultivariable analysisb
OR (95% CI)P valueaOR (95% CI)P valueOR (95% CI)P valueaOR (95% CI)P value
Age1.05 (1.04 to 1.06)<0.0011.04 (1.03 to 1.05)<0.0011.03 (1.01 to 1.04)<0.001
Male sex1.78 (1.33 to 2.38)<0.0011.32 (0.79 to 2.20)0.29
Diabetes mellitus4.43 (3.23 to 6.08)<0.0012.03 (1.41 to 2.92)<0.0014.38 (2.40 to 8.01)<0.0012.23 (1.11 to 4.48)0.03
Hypertension5.86 (4.31 to 7.95)<0.0011.54 (1.04 to 2.29)0.033.94 (2.31 to 6.72)<0.0013.03 (1.63 to 5.62)<0.001
Use of antiviral agents0.49 (0.28 to 0.83)0.00811.21 (2.72 to 46.21)0.00111.06 (2.66 to 45.98)0.001
Use of corticosteroid0.50 (0.34 to 0.74)<0.0013.31 (1.66 to 6.62)0.001
Baseline creatinine1.02 (1.01 to 1.02)<0.0011.01 (1.00 to 1.01)<0.0011.02 (1.01 to 1.03)0.001
  • A total of 20 patients who received RRT at diagnosis of SARS-CoV were not included in the analysis.

  • a P value = 0.77 for Hosmer-Lemeshow goodness-of-fit test, which did not indicate significant poor fit.

  • b P value = 0.19 for Hosmer-Lemeshow goodness-of-fit test, which did not indicate significant poor fit.