Table 3.

Graft survival, RMST, and DMRST at 5- and 10-yr post-biopsy, according to each cluster and each Banff diagnostic category (n=3510)

Banff Diagnosis% Graft Survival At 5 Yr (%)% Graft Survival At 10 Yr (%)RMST At 5 Yr Postbiopsy, (95% CI)RMST at 10 Yr Postbiopsy, (95% CI)HR Versus No, (95% CI)HR P Value Versus YrDRMST At 5 Yr Versus No Rejection, (95% CI)DRMST At 10 Yr Versus No Rejection, (95% CI)
No rejection89.551.04.74 (4.63 to 4.85)9.01 (8.56 to 9.46)
Borderline changes83.142.34.66 (4.47 to 4.85)8.87 (8.04 to 9.7)1.27 (0.88 to 1.84)0.2010.08 (-0.06 to 0.22)0.14 (-0.24 to 0.53)
TCMR75.541.24.50 (4.27 to 4.74)8.46 (7.7 to 9.22)1.66 (1.17 to 2.36)0.0040.24 (0.05 to 0.42)0.55 (0.09 to 1.01)
ABMR70.222.04.26 (3.89 to 4.63)7.63 (6.25 to 9.02)2.63 (1.65 to 4.21)<0.00010.48 (0.15 to 0.81)1.38 (0.51 to 2.25)
Mixed borderline rejection63.68.33.55 (4.06 to 4.57)6.74 (4.06 to 7.72)4.26 (2.29 to 7.94)<0.00010.67 (0.06 to 1.28)2.13 (0.65 to 3.61)
Mixed rejection59.220.53.98 (3.48 to 4.48)7.03 (5.74 to 8.32)3.24 (2.08 to 5.05)<0.00010.76 (0.34 to 1.18)1.98 (1.00 to 2.96)
Average0.45 (0.11 to 0.78)1.24 (0.40 to 2.07)
Weighted average0.29 (0.06 to 0.53)0.72 (0.14 to 0.93)
Cluster% Graft Survival at 5 Yr (%)% Graft Survival at 10 Yr (%)RMST at 5 Yr Postbiopsy (95% CI)RMST at 10 Yr Postbiopsy (95% CI)HR Versus Cluster 1HR P Value Versus Cluster 1DRMST At 5 Yr Versus Cluster 1 (95% CI)DRMST At 10 Yr Versus Cluster 1 (95% CI)
Cluster 190.954.64.76 (4.65 to 4.87)9.09 (8.63 to 9.56)
Cluster 277.633.34.42 (4.01 to 4.84)8.28 (6.98 to 9.59)1.98 (1.15 to 3.43)0.0140.34 (0.02 to 0.70)0.81 (−0.03 to 1.65)
Cluster 375.039.84.54 (4.30 to 4.79)8.56 (7.75 to 9.36)1.72 (1.17 to 2.52)0.0050.22 (0.02 to 0.41)0.53 (0.05 to 1.02)
Cluster 470.028.64.23 (3.87 to 4.58)7.67 (6.36 to 8.98)2.84 (1.88 to 4.30)<0.00010.53 (0.24 to 0.82)1.42 (0.69 to 2.15)
Cluster 562.36.14.06 (3.48 to 4.64)6.84 (5.04 to 8.64)4.17 (2.48 to 7.03)<0.00010.70 (0.26 to 1.14)2.25 (1.07 to 3.42)
Cluster 650.06.23.96 (3.43 to 4.48)6.78 (4.96 to 8.59)4.37 (2.59 to 7.35)<0.00010.80 (0.31 to 1.29)2.31 (1.11 to 3.52)
Average0.52 (0.17 to 0.87)1.46 (0.58 to 2.35)
Weighted average0.46 (0.09 to 0.69)1.25 (0.48 to 2.01)