Table 1.

Physiologic parameters after water restrictiona

Parameter and GroupDays of Water Restriction
1234
an = 4 for each group. C, control; WL, water-loaded; WR, water-restricted.
bP < 0.05 compared with control group.
cP < 0.05 compared with water-loaded group.
Urine volume (ml)
C4.3 ± 0.33.8 ± 0.53.5 ± 0.52.0 ± 0.4
WL22.6 ± 4.7b18.6 ± 4.9b18.8 ± 1.3b18.9 ± 2.9b
WR14.1 ± 2.6b7.7 ± 0.9b,c5.5 ± 0.5b,c2.6 ± 0.4c
Urine osmolality (mosmol/kg H2O)
C3983 ± 1354778 ± 5114139 ± 2124809 ± 479
WL953 ± 232b1063 ± 327b874 ± 43b830 ± 49b
WR1006 ± 87b1387 ± 54b1465 ± 157b,c1657 ± 119b,c
Plasma sodium (mmol/L)
C139.4 ± 1.1139.2 ± 1.1136.0 ± 1.1137.3 ± 0.5
WL100.8 ± 0.6b108.8 ± 0.6b98.7 ± 2.2b99.0 ± 0.2b
WR107.0 ± 0.7b,c115.1 ± 2.0b,c105.6 ± 3.2b115.4 ± 4.0b,c