Table 1.

Slopes of the linear regression curves between renal perfusion pressure and the excretory parametersa

GroupDiuresisNatriuresisFE WaterFE Sodium
aData are the mean ± SEM; FE, fractional excretion.
bP < 0.05 versus the control group.
cP < 0.05 versus the L-NAME-treated group.
Control5.14 ± 0.600.62 ± 0.070.28 ± 0.030.25 ± 0.03
L-NAME1.43 ± 0.25b0.19 ± 0.04b0.15 ± 0.03b0.13 ± 0.03b
L-NAME + low-dose candesartan2.27 ± 0.64b0.32 ± 0.08b0.16 ± 0.04b0.15 ± 0.04b
L-NAME + high-dose candesartan0.84 ± 0.24b0.15 ± 0.03b0.05 ± 0.02b,c0.06 ± 0.02b,c
L-NAME + captopril2.23 ± 0.35b0.28 ± 0.06b0.18 ± 0.03b0.16 ± 0.03b
L-NAME + verapamil1.87 ± 0.71b0.26 ± 0.09b0.13 ± 0.04b0.13 ± 0.03b