diabetic nephropathy

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Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin
Manga Motrapu, Monika Katarzyna Świderska, Irene Mesas, Julian Aurelio Marschner, Yutian Lei, Laura Martinez Valenzuela, Jia Fu, Kyung Lee, Maria Lucia Angelotti, Giulia Antonelli, Paola Romagnani, Hans-Joachim Anders and Lidia Anguiano

JASN August 2020, 31 (8) 1729-1745; DOI: https://doi.org/10.1681/ASN.2019070703

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Podocyte Integrin-β₃ and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy
Thati Madhusudhan, Sanchita Ghosh, Hongjie Wang, Wei Dong, Dheerendra Gupta, Ahmed Elwakiel, Stoyan Stoyanov, Moh’d Mohanad Al-Dabet, Shruthi Krishnan, Ronald Biemann, Sumra Nazir, Silke Zimmermann, Akash Mathew, Ihsan Gadi, Rajiv Rana, Jinyang Zeng-Brouwers, Marcus J. Moeller, Liliana Schaefer, Charles T. Esmon, Shrey Kohli, Jochen Reiser, Alireza R. Rezaie, Wolfram Ruf and Berend Isermann

JASN August 2020, 31 (8) 1762-1780; DOI: https://doi.org/10.1681/ASN.2019111163

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Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid–Mediated Activation of G Protein–Coupled Receptors GPR43 and GPR109A
Yan Jun Li, Xiaochen Chen, Tony K. Kwan, Yik Wen Loh, Julian Singer, Yunzi Liu, Jin Ma, Jian Tan, Laurence Macia, Charles R. Mackay, Steven J. Chadban and Huiling Wu

JASN June 2020, 31 (6) 1267-1281; DOI: https://doi.org/10.1681/ASN.2019101029

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Role of Impaired Nutrient and Oxygen Deprivation Signaling and Deficient Autophagic Flux in Diabetic CKD Development: Implications for Understanding the Effects of Sodium-Glucose Cotransporter 2-Inhibitors
Milton Packer

JASN May 2020, 31 (5) 907-919; DOI: https://doi.org/10.1681/ASN.2020010010

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Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy
Jing Guo, Owen J. L. Rackham, Niina Sandholm, Bing He, Anne-May Österholm, Erkka Valo, Valma Harjutsalo, Carol Forsblom, Iiro Toppila, Maija Parkkonen, Qibin Li, Wenjuan Zhu, Nathan Harmston, Sonia Chothani, Miina K. Öhman, Eudora Eng, Yang Sun, Enrico Petretto, Per-Henrik Groop and Karl Tryggvason

JASN February 2020, 31 (2) 309-323; DOI: https://doi.org/10.1681/ASN.2019030289

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Loss of Histone H3 K79 Methyltransferase Dot1l Facilitates Kidney Fibrosis by Upregulating Endothelin 1 through Histone Deacetylase 2
Long Zhang, Lihe Chen, Chao Gao, Enuo Chen, Andrea R. Lightle, Llewellyn Foulke, Bihong Zhao, Paul J. Higgins and Wenzheng Zhang

JASN February 2020, 31 (2) 337-349; DOI: https://doi.org/10.1681/ASN.2019070739

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Biologic Underpinnings of Type 1 Diabetic Kidney Disease
John R. Sedor and Barry I. Freedman

JASN October 2019, 30 (10) 1782-1783; DOI: https://doi.org/10.1681/ASN.2019080803

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Computational Segmentation and Classification of Diabetic Glomerulosclerosis
Brandon Ginley, Brendon Lutnick, Kuang-Yu Jen, Agnes B. Fogo, Sanjay Jain, Avi Rosenberg, Vighnesh Walavalkar, Gregory Wilding, John E. Tomaszewski, Rabi Yacoub, Giovanni Maria Rossi and Pinaki Sarder

JASN October 2019, 30 (10) 1953-1967; DOI: https://doi.org/10.1681/ASN.2018121259

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Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen
Rany M. Salem, Jennifer N. Todd, Niina Sandholm, Joanne B. Cole, Wei-Min Chen, Darrell Andrews, Marcus G. Pezzolesi, Paul M. McKeigue, Linda T. Hiraki, Chengxiang Qiu, Viji Nair, Chen Di Liao, Jing Jing Cao, Erkka Valo, Suna Onengut-Gumuscu, Adam M. Smiles, Stuart J. McGurnaghan, Jani K. Haukka, Valma Harjutsalo, Eoin P. Brennan, Natalie van Zuydam, Emma Ahlqvist, Ross Doyle, Tarunveer S. Ahluwalia, Maria Lajer, Maria F. Hughes, Jihwan Park, Jan Skupien, Athina Spiliopoulou, Andrew Liu, Rajasree Menon, Carine M. Boustany-Kari, Hyun M. Kang, Robert G. Nelson, Ronald Klein, Barbara E. Klein, Kristine E. Lee, Xiaoyu Gao, Michael Mauer, Silvia Maestroni, Maria Luiza Caramori, Ian H. de Boer, Rachel G. Miller, Jingchuan Guo, Andrew P. Boright, David Tregouet, Beata Gyorgy, Janet K. Snell-Bergeon, David M. Maahs, Shelley B. Bull, Angelo J. Canty, Colin N.A. Palmer, Lars Stechemesser, Bernhard Paulweber, Raimund Weitgasser, Jelizaveta Sokolovska, Vita Rovīte, Valdis Pīrāgs, Edita Prakapiene, Lina Radzeviciene, Rasa Verkauskiene, Nicolae Mircea Panduru, Leif C. Groop, Mark I. McCarthy, Harvest F. Gu, Anna Möllsten, Henrik Falhammar, Kerstin Brismar, Finian Martin, Peter Rossing, Tina Costacou, Gianpaolo Zerbini, Michel Marre, Samy Hadjadj, Amy J. McKnight, Carol Forsblom, Gareth McKay, Catherine Godson, A. Peter Maxwell, Matthias Kretzler, Katalin Susztak, Helen M. Colhoun, Andrzej Krolewski, Andrew D. Paterson, Per-Henrik Groop, Stephen S. Rich, Joel N. Hirschhorn, Jose C. Florez and SUMMIT Consortium, DCCT/EDIC Research Group, GENIE Consortium

JASN October 2019, 30 (10) 2000-2016; DOI: https://doi.org/10.1681/ASN.2019030218

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Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes
Helen C. Looker, Michael Mauer, Pierre-Jean Saulnier, Jennifer L. Harder, Viji Nair, Carine M. Boustany-Kari, Paolo Guarnieri, Jon Hill, Cordell A. Esplin, Matthias Kretzler, Robert G. Nelson and Behzad Najafian

JASN June 2019, 30 (6) 1049-1059; DOI: https://doi.org/10.1681/ASN.2018111166

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