focal segmental glomerulosclerosis

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Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice
Eugen Widmeier, Merlin Airik, Hannah Hugo, David Schapiro, Johannes Wedel, Chandra C. Ghosh, Makiko Nakayama, Ronen Schneider, Agape M. Awad, Anish Nag, Jang Cho, Markus Schueler, Catherine F. Clarke, Rannar Airik and Friedhelm Hildebrandt

JASN March 2019, 30 (3) 393-405; DOI: https://doi.org/10.1681/ASN.2018060625

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DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS
Howard Trachtman, Peter Nelson, Sharon Adler, Kirk N. Campbell, Abanti Chaudhuri, Vimal Kumar Derebail, Giovanni Gambaro, Loreto Gesualdo, Debbie S. Gipson, Jonathan Hogan, Kenneth Lieberman, Brad Marder, Kevin Edward Meyers, Esmat Mustafa, Jai Radhakrishnan, Tarak Srivastava, Miganush Stepanians, Vladimír Tesar, Olga Zhdanova, Radko Komers and on behalf of the DUET Study Group

JASN November 2018, 29 (11) 2745-2754; DOI: https://doi.org/10.1681/ASN.2018010091

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The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes
Gentzon Hall, Brandon M. Lane, Kamal Khan, Igor Pediaditakis, Jianqiu Xiao, Guanghong Wu, Liming Wang, Maria E. Kovalik, Megan Chryst-Stangl, Erica E. Davis, Robert F. Spurney and Rasheed A. Gbadegesin

JASN August 2018, 29 (8) 2110-2122; DOI: https://doi.org/10.1681/ASN.2017121338

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Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome
Hanna Debiec, Claire Dossier, Eric Letouzé, Christopher E. Gillies, Marina Vivarelli, Rosemary K. Putler, Elisabet Ars, Evelyne Jacqz-Aigrain, Valery Elie, Manuela Colucci, Stéphanie Debette, Philippe Amouyel, Siham C. Elalaoui, Abdelaziz Sefiani, Valérie Dubois, Tabassome Simon, Matthias Kretzler, Jose Ballarin, Francesco Emma, Matthew G. Sampson, Georges Deschênes and Pierre Ronco

JASN July 2018, 29 (7) 2000-2013; DOI: https://doi.org/10.1681/ASN.2017111185

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Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension
Yosu Luque, Olivia Lenoir, Philippe Bonnin, Lise Hardy, Anna Chipont, Sandrine Placier, Sophie Vandermeersch, Yi-Chun Xu-Dubois, Blaise Robin, Hélène Lazareth, Michèle Souyri, Léa Guyonnet, Véronique Baudrie, Eric Camerer, Eric Rondeau, Laurent Mesnard and Pierre-Louis Tharaux

JASN December 2017, 28 (12) 3563-3578; DOI: https://doi.org/10.1681/ASN.2016090960

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Variations in MicroRNA-25 Expression Influence the Severity of Diabetic Kidney Disease
Yunshuang Liu, Hongzhi Li, Jieting Liu, Pengfei Han, Xuefeng Li, He Bai, Chunlei Zhang, Xuelian Sun, Yanjie Teng, Yufei Zhang, Xiaohuan Yuan, Yanhui Chu and Binghai Zhao

JASN December 2017, 28 (12) 3627-3638; DOI: https://doi.org/10.1681/ASN.2015091017

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Targeting mTOR Signaling Can Prevent the Progression of FSGS
Stefan Zschiedrich, Tillmann Bork, Wei Liang, Nicola Wanner, Kristina Eulenbruch, Stefan Munder, Björn Hartleben, Oliver Kretz, Simon Gerber, Matias Simons, Amandine Viau, Martine Burtin, Changli Wei, Jochen Reiser, Nadja Herbach, Maria-Pia Rastaldi, Clemens D Cohen, Pierre-Louis Tharaux, Fabiola Terzi, Gerd Walz, Markus Gödel and Tobias B Huber

JASN July 2017, 28 (7) 2144-2157; DOI: https://doi.org/10.1681/ASN.2016050519

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Sildenafil Prevents Podocyte Injury via PPAR-γ–Mediated TRPC6 Inhibition
Ramon Sonneveld, Joost G. Hoenderop, Andrea M. Isidori, Carole Henique, Henry B. Dijkman, Jo H. Berden, Pierre-Louis Tharaux, Johan van der Vlag and Tom Nijenhuis

JASN May 2017, 28 (5) 1491-1505; DOI: https://doi.org/10.1681/ASN.2015080885

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Thrombotic Microangiopathy in Inverted Formin 2–Mediated Renal Disease
Rachel C. Challis, Troels Ring, Yaobo Xu, Edwin K.S. Wong, Oliver Flossmann, Ian S.D. Roberts, Saeed Ahmed, Michael Wetherall, Giedrius Salkus, Vicky Brocklebank, Julian Fester, Lisa Strain, Valerie Wilson, Katrina M. Wood, Kevin J. Marchbank, Mauro Santibanez-Koref, Timothy H.J. Goodship and David Kavanagh

JASN April 2017, 28 (4) 1084-1091; DOI: https://doi.org/10.1681/ASN.2015101189

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Most ApoL1 Is Secreted by the Liver
Khuloud Shukha, Jessica L. Mueller, Raymond T. Chung, Michael P. Curry, David J. Friedman, Martin R. Pollak and Anders H. Berg

JASN April 2017, 28 (4) 1079-1083; DOI: https://doi.org/10.1681/ASN.2016040441

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