focal segmental glomerulosclerosis

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TRPC6 Binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility
Louise K. Farmer, Ruth Rollason, Daniel J. Whitcomb, Lan Ni, Alexander Goodliff, Abigail C. Lay, Lutz Birnbaumer, Kate J. Heesom, Shang-Zhong Xu, Moin A. Saleem and Gavin I. Welsh

JASN October 2019, 30 (10) 1910-1924; DOI: https://doi.org/10.1681/ASN.2018070729

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APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore
Shrijal S. Shah, Herbert Lannon, Leny Dias, Jia-Yue Zhang, Seth L. Alper, Martin R. Pollak and David J. Friedman

JASN September 2019, ASN.2019020114; DOI: https://doi.org/10.1681/ASN.2019020114

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Contribution of Coiled-Coil Assembly to Ca²⁺/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes
Onur K. Polat, Masatoshi Uno, Terukazu Maruyama, Ha Nam Tran, Kayo Imamura, Chee Fah Wong, Reiko Sakaguchi, Mariko Ariyoshi, Kyohei Itsuki, Jun Ichikawa, Takashi Morii, Masahiro Shirakawa, Ryuji Inoue, Katsuhiko Asanuma, Jochen Reiser, Hidehito Tochio, Yasuo Mori and Masayuki X. Mori

JASN September 2019, 30 (9) 1587-1603; DOI: https://doi.org/10.1681/ASN.2018070756

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Contributions of Rare Gene Variants to Familial and Sporadic FSGS
Minxian Wang, Justin Chun, Giulio Genovese, Andrea U. Knob, Ava Benjamin, Maris S. Wilkins, David J. Friedman, Gerald B. Appel, Richard P. Lifton, Shrikant Mane and Martin R. Pollak

JASN September 2019, 30 (9) 1625-1640; DOI: https://doi.org/10.1681/ASN.2019020152

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Apoptotic Cell–Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN
Poh-Yi Gan, Andrea S. Godfrey, Joshua D. Ooi, Kim-Maree O’Sullivan, Virginie Oudin, A. Richard Kitching and Stephen R. Holdsworth

JASN August 2019, 30 (8) 1365-1374; DOI: https://doi.org/10.1681/ASN.2018090955

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Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS
Kristina M. Niculovic, Linda Blume, Henri Wedekind, Elina Kats, Iris Albers, Stephanie Groos, Markus Abeln, Jessica Schmitz, Esther Beuke, Jan H. Bräsen, Anette Melk, Mario Schiffer, Birgit Weinhold and Anja K. Münster-Kühnel

JASN June 2019, 30 (6) 1021-1035; DOI: https://doi.org/10.1681/ASN.2018090951

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Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice
Eugen Widmeier, Merlin Airik, Hannah Hugo, David Schapiro, Johannes Wedel, Chandra C. Ghosh, Makiko Nakayama, Ronen Schneider, Agape M. Awad, Anish Nag, Jang Cho, Markus Schueler, Catherine F. Clarke, Rannar Airik and Friedhelm Hildebrandt

JASN March 2019, 30 (3) 393-405; DOI: https://doi.org/10.1681/ASN.2018060625

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DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS
Howard Trachtman, Peter Nelson, Sharon Adler, Kirk N. Campbell, Abanti Chaudhuri, Vimal Kumar Derebail, Giovanni Gambaro, Loreto Gesualdo, Debbie S. Gipson, Jonathan Hogan, Kenneth Lieberman, Brad Marder, Kevin Edward Meyers, Esmat Mustafa, Jai Radhakrishnan, Tarak Srivastava, Miganush Stepanians, Vladimír Tesar, Olga Zhdanova, Radko Komers and on behalf of the DUET Study Group

JASN November 2018, 29 (11) 2745-2754; DOI: https://doi.org/10.1681/ASN.2018010091

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The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes
Gentzon Hall, Brandon M. Lane, Kamal Khan, Igor Pediaditakis, Jianqiu Xiao, Guanghong Wu, Liming Wang, Maria E. Kovalik, Megan Chryst-Stangl, Erica E. Davis, Robert F. Spurney and Rasheed A. Gbadegesin

JASN August 2018, 29 (8) 2110-2122; DOI: https://doi.org/10.1681/ASN.2017121338

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Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome
Hanna Debiec, Claire Dossier, Eric Letouzé, Christopher E. Gillies, Marina Vivarelli, Rosemary K. Putler, Elisabet Ars, Evelyne Jacqz-Aigrain, Valery Elie, Manuela Colucci, Stéphanie Debette, Philippe Amouyel, Siham C. Elalaoui, Abdelaziz Sefiani, Valérie Dubois, Tabassome Simon, Matthias Kretzler, Jose Ballarin, Francesco Emma, Matthew G. Sampson, Georges Deschênes and Pierre Ronco

JASN July 2018, 29 (7) 2000-2013; DOI: https://doi.org/10.1681/ASN.2017111185

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